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Human MD-2 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB1787

R&D Systems, part of Bio-Techne
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MAB1787
MAB1787-SP

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

ELISA Development, Neutralization, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 288307

Product Specifications

Immunogen

E. coli-derived recombinant human MD-2
Glu17-Asn160
Accession # Q9Y6Y9

Specificity

Detects human MD-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross‑react with recombinant human MD-1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human MD-2 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human MD-2 (Catalog # 1787-MD)
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 4 using MAB1787 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: MD2

MD-2, also known as lymphocyte antigen 96 and ESOP-1, is a secreted glycoprotein that associates with the extracellular domain of TLR4. MD-2 is required for LPS binding and subsequent TLR4 signaling.

Long Name

Myeloid Differentiation Protein 2/Lymphocyte Antigen 96

Alternate Names

ESOP-1, LY96, MD-2

Entrez Gene IDs

23643 (Human); 17087 (Mouse); 102118398 (Cynomolgus Monkey)

Gene Symbol

LY96

UniProt

Additional MD2 Products

Product Documents for Human MD-2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human MD-2 Antibody

For research use only

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