Human/Mouse Otoraplin/OTOR Antibody
R&D Systems, part of Bio-Techne | Catalog # AF3979
Key Product Details
Species Reactivity
Human, Mouse
Applications
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
E. coli-derived recombinant human Otoraplin/OTOR
Val18-Glu128
Accession # Q9NRC9
Val18-Glu128
Accession # Q9NRC9
Specificity
Detects human and mouse Otoraplin/OTOR in direct ELISAs and Western blots.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Human/Mouse Otoraplin/OTOR Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Human and Mouse Otoraplin/OTOR
Sample: Recombinant Human and Mouse Otoraplin/OTOR
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Otoraplin/OTOR
Otoraplin (OTOR), also known as fibrocyte-derived protein (Fdp) and Melanoma inhibitory activity-like (MIAL), is a secreted 16 kDa globular protein that is preferentially expressed in the inner ear by periotic mesenchyme and developing and mature fibrocytes. It is highly homologous to MIA/cartilage-derived retinoic acid‑sensitive protein (CD-RAP), which is a cartilage-specific protein that is also expressed in malignant melanoma cells. The 111 amino acid residue (aa) mature human otoraplin contains one SH3 domain (aa 46‑107) and a Tyr at position 50 that is reportedly sulfated. Otoraplin is reported to play a role in the initiation of periotic mesenchyme chondrogenesis. Mature human Otoraplin shares 91% and 89% aa sequence identity with canine and mouse Otoraplin, respectively.
Alternate Names
MIAL1, OTOR
Gene Symbol
OTOR
UniProt
Additional Otoraplin/OTOR Products
Product Documents for Human/Mouse Otoraplin/OTOR Antibody
Product Specific Notices for Human/Mouse Otoraplin/OTOR Antibody
For research use only
Loading...
Loading...
Loading...
Loading...