Human/Mouse Serpin I1 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB3124
Key Product Details
Species Reactivity
Human, Mouse
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG2A Clone # 437016
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Serpin I1
Ala19-Leu410
Accession # AAH18043
Ala19-Leu410
Accession # AAH18043
Specificity
Detects human and mouse SerpinI1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross reactivity with recombinant mouse Serpin I1 is observed and no cross-reactivity with recombinant human Serpin A1, A3, A4, A5, A12, B6, B8, B9, C1, D1, F2, G1, or I2 is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Human/Mouse Serpin I1 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Human and Mouse Serpin I1
Sample: Recombinant Human and Mouse Serpin I1
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Serpin I1
Serpin I1, also known as neuroserpin, is a secreted serine protease inhibitor predominantly expressed in the brain. Serpin I1 defects cause familial encephalopathy with neuroserpin inclusion bodies (FEN1B), an autosomal dominant dementia. The amino acid sequence of human Serpin I1 is 99%, 93%, 88%, 86% and 80% identical to that of chimpanzee, dog, rat, mouse and chicken.
Alternate Names
Neuroserpin, PI12
Gene Symbol
SERPINI1
UniProt
Additional Serpin I1 Products
Product Documents for Human/Mouse Serpin I1 Antibody
Product Specific Notices for Human/Mouse Serpin I1 Antibody
For research use only
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