Human MS4A3 Fluorescein-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB6247F
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Fluorescein (Excitation = 488 nm, Emission = 515-545 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 489433
Product Specifications
Immunogen
NS0 mouse myeloma cell line transfected with human MS4A3
Accession # NP_006129
Accession # NP_006129
Specificity
Detects human MS4A3 in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human MS4A3 Fluorescein-conjugated Antibody
Detection of MS4A3 in Human Whole Blood Monocytes by Flow Cytometry.
Human whole blood monocytes were stained with Mouse Anti-Human MS4A3 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB6247F, filled histogram) or isotype control antibody (Catalog # IC003F, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Human MS4A3 Fluorescein-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human whole blood monocytes
Sample: Human whole blood monocytes
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: MS4A3
MS4A3, also known as HTm4, is an membrane protein that is a member of the MS4A family of four-transmembrane proteins that also includes CD20 and Fc epsilonRI beta. MS4A3 is a cell cycle regulator expressed in the perinuclear area of human basophils, eosinophils, early embryonic neural progenitors, splenic red pulp macrophages, monocytes and bile duct plus pancreatic duct epithelium. The C-terminal region of MS4A3 interacts with cdc-associated phosphatase (KAP), enhancing its activity on cyclin-dependent kinase 2 (cdk2) and facilitating G(0)/G(1) arrest. The combined non-membrane segments of the 214 amino acid (aa), 22-25 kDa human MS4A3 show 53% and 52% aa identity with corresponding regions of mouse and rat MS4A3, respectively.
Long Name
Membrane-spanning 4-domains, Subfamily A, Member 3 [Hematopoietic Cell-specific]
Alternate Names
CD20L, HTM4
Gene Symbol
MS4A3
UniProt
Additional MS4A3 Products
Product Documents for Human MS4A3 Fluorescein-conjugated Antibody
Product Specific Notices for Human MS4A3 Fluorescein-conjugated Antibody
For research use only
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