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Human MyD88 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB2928

R&D Systems, part of Bio-Techne
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MAB2928
MAB2928-SP

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 316603

Product Specifications

Immunogen

E. coli-derived recombinant human MyD88
Met1-Pro296
Accession # Q99836

Specificity

Detects human MyD88 in direct ELISAs. Does not cross-react with mouse MyD88.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Scientific Data Images for Human MyD88 Antibody

MyD88 antibody in Raji Human Cell Line by Immunocytochemistry (ICC).

MyD88 in Raji Human Cell Line.

MyD88 was detected in immersion fixed Raji human Burkitt's lymphoma cell line using Rat Anti-Human MyD88 Monoclonal Antibody (Catalog # MAB2928) at 3 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Applications for Human MyD88 Antibody

Application
Recommended Usage

Immunocytochemistry

3-25 µg/mL
Sample: Immersion fixed Raji human Burkitt's lymphoma cell line and human peripheral blood mononuclear cells
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: MyD88

MyD88 was first identified as a myeloid differentiation primary response protein. It contains a cytoplasmic Toll/interleukin 1 receptor (TIR) domain that classifies it as a member of the TIR superfamily. MyD88 is expressed in many adult tissues including heart, kidney and liver tissue and in monocyte, T, B, NK and dendritic cells.

Long Name

Myeloid Differentiation Primary Response Gene 88

Alternate Names

MYD88D, myeloid differentiation primary response gene (88), myeloid differentiation primary response protein MyD88

Entrez Gene IDs

4615 (Human); 17874 (Mouse)

Gene Symbol

MYD88

UniProt

Additional MyD88 Products

Product Documents for Human MyD88 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human MyD88 Antibody

For research use only

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