Human NgR3/NgRH2 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB2920

R&D Systems, part of Bio-Techne
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MAB2920
MAB2920-SP
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 319123

View all NgR3/NgRH2 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human NgR3/NgRH2
Cys25-Ala419
Accession # Q86UN2

Specificity

Detects human NgR3/NgRH2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human NgRH1 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human NgR3/NgRH2 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human NgR3/NgRH2

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
Size / Price
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: NgR3/NgRH2

NgR3, a Nogo-66 receptor homolog alternately known as reticulon 4 receptor-like 1, Nogo receptor homolog 2 (NgRH2), or NgR3, is an approximately 60 kDa glycosylphosphatidylinositol-anchored glycoprotein expressed primarily in the brain. It contains eight leucine-rich repeats (LRR) flanked by conserved cysteines. Although LRR are typically involved in protein-protein interactions, NgR3 has not been shown to bind known Nogo-66 receptor ligands. Mature human NgR3 shares 88%, 88%, 48% and 44% amino acid identity with mature mouse NgR3, rat NgR3, human NgRH1 and human NgR, respectively.

Long Name

Nogo-66 Receptor-related Protein 3/Nogo-66 Receptor Homolog 2/Reticulon-4 Receptor-like 1

Alternate Names

NgRH2, RTN4RL1

Entrez Gene IDs

146760 (Human); 237847 (Mouse)

Gene Symbol

RTN4RL1

UniProt

Q86UN2

Additional NgR3/NgRH2 Products

Product Documents for Human NgR3/NgRH2 Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human NgR3/NgRH2 Antibody

For research use only

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