Human Opticin Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB3148
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG2A Clone # 361328
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Opticin
Ala20-Thr332
Accession # Q9UBM4
Ala20-Thr332
Accession # Q9UBM4
Specificity
Detects human Opticin in direct ELISAs and Western blots. In direct ELIAs and Western blots, no cross-reactivity with recombinant mouse Opticin is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Human Opticin Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Human Opticin
Sample: Recombinant Human Opticin
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Opticin
Opticin (Oculoglycan) is a member of the small leucine-rich proteoglycan (SLRP) family with homology to class III extracellular matrix family members Epiphycan and Mimecan. It forms a 90 kDa noncovalent dimer that is a component of vitreous collagen fibrils in the eye and is also expressed in the retina, iris, ligaments and skin. Mature human Opticin shares 73% and 65% aa identity with mouse and rat, respectively. Mutations of Opticin have been associated with age-related macular degeneration.
Alternate Names
Oculogylcan, OPTC
Gene Symbol
OPTC
UniProt
Additional Opticin Products
Product Documents for Human Opticin Antibody
Product Specific Notices for Human Opticin Antibody
For research use only
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