Human P2X7/P2RX7 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB97903
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2A Clone # 1058613
Product Specifications
Immunogen
Human P2X7/P2RX7 synthetic peptide
Accession # Q99572
Accession # Q99572
Specificity
Detects human P2X7/P2RX7 in direct ELISA.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human P2X7/P2RX7 Antibody
Detection of P2X7/P2RX7 in Hek 293 cells transfected with Human P2RX7 peptide and eGFP by Flow Cytometry.
Hek293 cells transfected with Human P2RX7 peptide and eGFP were stained with either (A) Mouse Anti-Human P2X7/P2RX7 Monoclonal Antibody (Catalog # MAB97903) or (B) Mouse IgG2B Isotype Control (Catalog # MAB004) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B). View our protocol for Staining Membrane-associated Proteins.Applications for Human P2X7/P2RX7 Antibody
Application
Recommended Usage
Flow Cytometry
0.25 µg/106 cells
Sample: Hek 293 cells transfected with Human P2RX7 peptide and eGFP
Sample: Hek 293 cells transfected with Human P2RX7 peptide and eGFP
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: P2X7/P2RX7
Human P2X purinoceptor 7 (aka P2X7) is a 595 aminoacids (aa) protein encoded by the P2RX7 gene. P2X7 receptors belong to the family of ATP-gated ion channels, and their activity can be found in cells of hemopoietic lineage including macrophages, microglia, and certain lymphocytes. They mediate the influx of Ca2+ and Na+ and the release of pro-inflammatory cytokines. At least 8 different human P2X7 isoforms formed by alternative splicing have been reported, ranging from 128 aa to 595 aa. The P2X7 subunits can form homomeric receptors only with a typical P2X receptor structure.
Long Name
P2X Purinergic Receptor 7
Alternate Names
P2RX7
Gene Symbol
P2RX7
UniProt
Additional P2X7/P2RX7 Products
Product Documents for Human P2X7/P2RX7 Antibody
Product Specific Notices for Human P2X7/P2RX7 Antibody
For research use only
Loading...
Loading...
Loading...
Loading...
Loading...