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Human Pax3 Antibody

R&D Systems, part of Bio-Techne | Catalog # AF2457

R&D Systems, part of Bio-Techne
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AF2457
AF2457-SP

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Avian - Chicken

Applications

Validated:

Immunocytochemistry, Western Blot

Cited:

Immunocytochemistry, Immunohistochemistry

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

E. coli-derived recombinant human Pax3
Met1-Ser215
Accession # NP_000429

Specificity

Detects Pax3 in direct ELISAs and Western blots. In Western blots, approximately 2% cross-reactivity with recombinant human (rh) Pax5 and 1% rhPax7, under reducing conditions, is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Pax3 Antibody

Application
Recommended Usage

Immunocytochemistry

5-15 µg/mL
Sample: Immersion fixed B16-F1 mouse melanoma cell line

Western Blot

0.1 µg/mL
Sample: Recombinant Human Pax3

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Pax3

Pax3 belongs to the family of paired box transcription factors. Pax family proteins typically contain a paired box domain and a paired-type homeodomain. These transcription factors play critical roles during fetal development. There is 98% homology between human and mouse Pax3.

Long Name

Paired Box Gene 3 [Waardenburg Syndrome 1]

Alternate Names

HUP2, WS1

Entrez Gene IDs

5077 (Human); 18505 (Mouse)

Gene Symbol

PAX3

UniProt

Additional Pax3 Products

Product Documents for Human Pax3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Pax3 Antibody

For research use only

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