Human Porimin Antibody
R&D Systems, part of Bio-Techne | Catalog # AB3010
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry, Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Porimin
His27-Ser149
Accession # AAG21694
His27-Ser149
Accession # AAG21694
Specificity
Detects human Porimin in direct ELISAs and Western blots.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Human Porimin Antibody
Application
Recommended Usage
Flow Cytometry
0.25 µg/106 cells
Sample: Jurkat human acute T cell leukemia cell line
Sample: Jurkat human acute T cell leukemia cell line
Western Blot
1 µg/mL
Sample: Recombinant Human Porimin
Sample: Recombinant Human Porimin
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Reconstitution
Reconstitute at 1 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Porimin
Human Porimin is a 55‑110 kDa type I transmembrane (TM) glycoprotein that belongs to a mucin family. The ECD contains 45% serine and threonine and has multiple N- and O-linked glycosylation sites. The cytoplasmic tail contains a lysosome-targeting motif. Porimin activation induces cell death. The amino acid sequence of human Porimin ECD is 40% identical to that of mouse, rat and canine, respectively.
Long Name
Pro-Oncosis Receptor Inducing Membrane Injury
Alternate Names
KCT3, TMEM123
Entrez Gene IDs
114908 (Human)
Gene Symbol
TMEM123
UniProt
Additional Porimin Products
Product Documents for Human Porimin Antibody
Product Specific Notices for Human Porimin Antibody
For research use only
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