Human Prokineticin R1/PKR1 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB4655
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
CyTOF-ready, Flow Cytometry
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # 420849
Product Specifications
Immunogen
NS0 mouse myeloma cell line transfected with human Prokineticin R1/PKR1
Met1-Lys393
Accession # Q8TCW9
Met1-Lys393
Accession # Q8TCW9
Specificity
Detects human Prokineticin R1/PKR1. Stains human Prokineticin R1/PKR1 transfectants but not irrelevant transfectants.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Scientific Data Images for Human Prokineticin R1/PKR1 Antibody
Detection of Prokineticin R1/PKR1 in Human Monocytes by Flow Cytometry.
Human blood-derived monocytes were stained with Human Prokineticin R1/PKR1 Monoclonal Antibody (Catalog # MAB4655, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (Catalog # F0101B).Applications for Human Prokineticin R1/PKR1 Antibody
Application
Recommended Usage
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
Flow Cytometry
2.5 µg/106 cells
Sample: Human blood-derived monocytes
Sample: Human blood-derived monocytes
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Prokineticin R1/PROKR1
Prokineticin Receptor 1 (PKR1), also called ZAQ or GPR73a (G-protein coupled receptor 73a), is a 7-transmembrane glycoprotein of the GPCR family. The extracellular portions of human PKR1 share 81% and 78% aa identity with corresponding portions of mouse PKR1 and human PKR2, with non-identity mainly in the N‑terminal sequences. Both PKR1 and PKR2 mediate the effects of prokineticins 1 and 2. This includes mitogenic regulation of angiogenesis in endocrine glands and stimulation of contraction in gastrointestinal smooth muscle.
Long Name
Prokineticin Receptor 1
Alternate Names
GPR73, GPR73a, PKR1, ProkineticinR1, PROKR1, ZAQ
Gene Symbol
PROKR1
UniProt
Additional Prokineticin R1/PROKR1 Products
Product Documents for Human Prokineticin R1/PKR1 Antibody
Product Specific Notices for Human Prokineticin R1/PKR1 Antibody
For research use only
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