Human ROR gamma/RORC/NR1F3 Antibody

R&D Systems, part of Bio-Techne | Catalog # PP-H6437-00

R&D Systems, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Direct ELISA, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # H6437

View all ROR gamma/RORC/NR1F3 Antibodies »

Product Summary for Human ROR gamma/RORC/NR1F3 Antibody

Immunogen

Recombinant human ROR gamma/RORC/NR1F3

Specificity

This antibody specifically recognizes human ROR gamma and does not cross-react with human ROR alpha or human ROR beta. Not yet tested in other species.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human ROR gamma/RORC/NR1F3 Antibody

Application
Recommended Usage

Direct ELISA

This antibody can be used at 0.3 μg/mL with the appropriate secondary reagents to detect human ROR gamma.

Immunoprecipitation

Optimal dilutions should be determined by each laboratory.

Western Blot

This antibody can be used at 1 μg/mL under reducing conditions with the appropriate secondary reagents to detect human ROR gamma.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: ROR gamma/RORC/NR1F3

Retinoic acid-related Orphan Receptor gamma (ROR gamma, TOR, RORC; NR1F3) is a member of the Orphan Nuclear Receptor family. ROR gamma is expressed in the muscle, thymus, testis, pancreas, prostate, heart and liver. ROR gamma plays a role in thymocyte development and homeostasis. RORs bind to DNA as monomers on half-site elements with 5' A/T-rich extension. An N-terminal isoform of ROR gamma, ROR gammat, has been shown to be specifically expressed in the thymus.

Long Name

Retinoic Acid-Related Orphan Receptor gamma

Alternate Names

NR1F3, RORC, RZRG

Entrez Gene IDs

6097 (Human)

Gene Symbol

RORC

Additional ROR gamma/RORC/NR1F3 Products

Product Documents for Human ROR gamma/RORC/NR1F3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human ROR gamma/RORC/NR1F3 Antibody

For research use only

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