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Human S100A7 Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # BAF4475

R&D Systems, part of Bio-Techne
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BAF4475

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Sheep IgG

Product Specifications

Immunogen

E. coli-derived recombinant human S100A7
Met1-Gln101
Accession # AAA60210

Specificity

Detects human S100A7 in Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human S100A8 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Human S100A7 Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human S100A7

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: S100A7

S100A7 (also Psoriasin) is an 11-13 kDa member of the S101 family, EF-hand superfamily of Ca-binding proteins. It is produced by keratinocytes and exists as both an intracellular and extracellular polypeptide. Intercellularly, it binds to E/FABP and may participate in fatty acid metabolism. Extracellularly, it is both monomeric and heterooligomeric and exhibits antibacterial properties. Human S100A7 is 101 amino acids (aa) in length. It contains two EF-hand motifs (aa 13-48 and 50-85), three zinc-binding His residues, one high-affinity Ca-binding site (aa 63-74) and an overlapping antibacterial sequence (aa 35-80). There appear to be no meaningful rodent structural orthologs. Human S100A7 is 93% aa identical to human S100A15/7A, and the S100A7 gene has a duplication (S100A7B) that is 54% aa identical to S100A7.

Long Name

S100 Calcium Binding Protein A7

Alternate Names

PSOR1

Entrez Gene IDs

6278 (Human); 192344 (Mouse)

Gene Symbol

S100A7

UniProt

Additional S100A7 Products

Product Documents for Human S100A7 Biotinylated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human S100A7 Biotinylated Antibody

For research use only

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