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Human STRO-1 Alexa Fluor® 647-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB1038R

R&D Systems, part of Bio-Techne
Discontinued Product
FAB1038R has been discontinued. View all STRO-1 products.

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Alexa Fluor 647 (Excitation = 650 nm, Emission = 668 nm)

Antibody Source

Monoclonal Mouse IgM Clone # STRO-1

Product Specifications

Immunogen

Human CD34+ bone marrow cells

Specificity

Detects human STRO-1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgM

Scientific Data Images for Human STRO-1 Alexa Fluor® 647-conjugated Antibody

Detection of STRO-1 antibody in MG-63 Cell Line antibody by Flow Cytometry.

Detection of STRO-1 in MG-63 Cell Line by Flow Cytometry.

Human MG-63 osteosarcoma cell line was stained with Mouse Anti-Human STRO-1 Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB1038R, filled histogram) or Mouse IgM isotype control antibody (open histogram). View our protocol for Staining Membrane-associated Proteins.
Detection of STRO-1 antibody in Human Mesenchymal Stem Cells antibody by Flow Cytometry.

Detection of STRO-1 in Human Mesenchymal Stem Cells by Flow Cytometry.

Human mesenchymal stem cells were stained with (A) Mouse Anti-Human STRO-1 Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB1038R, filled histogram) or (B) Mouse IgM isotype control antibody and Mouse anti-Human CD90 Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB2067G). View our protocol for Staining Membrane-associated Proteins.

Applications for Human STRO-1 Alexa Fluor® 647-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

0.25-1 µg/106 cells
Sample: MG‑63 human osteosarcoma cell line and human mesenchymal stem cells

Reviewed Applications

Read 1 review rated 5 using FAB1038R in the following applications:

Formulation, Preparation, and Storage

Purification

IgM-specific Affinity-purified from hybridoma culture supernatant

Reconstitution

Reconstitution default not known

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: STRO-1

STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units-fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells (1). The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes (2).

References

  1. Simmons, P.J. and B. Torok-Storb (1991) Blood 78:55.
  2. Dennis, J.E. et al. (2002) Cells Tissues Organs 170:73.

Long Name

A Stromal Cell Precursor Surface Antigen

Alternate Names

STRO1

Additional STRO-1 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human STRO-1 Alexa Fluor® 647-conjugated Antibody


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

For research use only

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