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Human Thrombopoietin R/Tpo R APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB1016A

R&D Systems, part of Bio-Techne
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FAB1016A

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 167639

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Thrombopoietin R/Tpo R
Ser25-Tyr423
Accession # P40238

Specificity

Detects human Thrombopoietin R/Tpo R in Western blots. In Western blots, no cross-reactivity with recombinant mouse Tpo R or recombinant human Epo R is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Human Thrombopoietin R/Tpo R APC-conjugated Antibody

Detection of Thrombopoietin R/Tpo R antibody in TF-1 Human Cell Line antibody by Flow Cytometry.

Detection of Thrombopoietin R/Tpo R in TF‑1 Human Cell Line by Flow Cytometry.

TF-1 human erythroleukemic cell line was stained with Mouse Anti-Human Thrombopoietin R/Tpo R APC-conjugated Monoclonal Antibody (Catalog # FAB1016A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human Thrombopoietin R/Tpo R APC-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: TF‑1 human erythroleukemic cell line
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: Thrombopoietin R/Tpo R

Thrombopoietin R, also known as Tpo R, is a type I membrane protein belonging to the hematopoietin/cytokine receptor superfamily. Tpo R is expressed by hematopoietic progenitor cells, megakaryocytes and platelets and is involved in the regulation of megakaryocytopoiesis and thrombopoiesis.

Long Name

Thrombopoietin Receptor

Alternate Names

c-Mpl, CD110, MPL, MPLV, TpoR

Entrez Gene IDs

4352 (Human); 17480 (Mouse)

Gene Symbol

MPL

UniProt

Additional Thrombopoietin R/Tpo R Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Thrombopoietin R/Tpo R APC-conjugated Antibody

For research use only

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