Human Tryptase  alpha/TPS1 Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # BAF2370

R&D Systems, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG

View all Tryptase alpha/TPS1 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Tryptase alpha/TPS1
Ile31-Pro275
Accession # AAA86934

Specificity

Detects human Tryptase alpha/TPS1 in Western blots. In Western blots, approximately 60% cross-reactivity with recombinant human (rh) TPSB2 is observed and approximately 10% cross-reactivity with rhTPSG1 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Tryptase  alpha/TPS1 Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human Tryptase  alpha/TPS1
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Tryptase alpha/TPS1

Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase beta-1, also known as mast cell protease 7 (MCPT7), exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. Tryptase epsilon, also known as brain-specific serine protease 4 (BSSP-4) and brain serine protease 2 (BSP-2), is encoded by the PRSS22 gene and preferentially expressed in epithelium-rich tissues such as lung and eye. Tryptase gamma-1, also called transmembrane tryptase, is encoded by TPSG1, one of many serine protease genes clustered on human chromosome 16p13.3.

Alternate Names

alpha-Tryptase, TPS1, TPSAB1, Tryptase 1

Entrez Gene IDs

7177 (Human)

Gene Symbol

TPSAB1

UniProt

AAA86934

Additional Tryptase alpha/TPS1 Products

Product Documents for Human Tryptase  alpha/TPS1 Biotinylated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Tryptase  alpha/TPS1 Biotinylated Antibody

For research use only

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