Hyaluronan synthase 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05924

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP3-05924-100ul
NBP3-05924-50ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Hyaluronan synthase 1 Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with E. coli-derived Human Hyaluronan synthase 1 fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Hyaluronan synthase 1 Antibody

Immunohistochemistry-Paraffin: Hyaluronan synthase 1 Antibody [NBP3-05924]

Immunohistochemistry-Paraffin: Hyaluronan synthase 1 Antibody [NBP3-05924]

Immunohistochemistry-Paraffin: Hyaluronan synthase 1 Antibody [NBP3-05924] - Staining of human HAS1 in human smooth muscle with rabbit polyclonal antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: Hyaluronan synthase 1 Antibody [NBP3-05924]

Immunohistochemistry-Paraffin: Hyaluronan synthase 1 Antibody [NBP3-05924]

Immunohistochemistry-Paraffin: Hyaluronan synthase 1 Antibody [NBP3-05924] - staining of human HAS1 in human kidney with rabbit polyclonal antibody at 1:500 dilution.

Applications for Hyaluronan synthase 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200-1:1000

Immunohistochemistry-Paraffin

1:200-1:1000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Hyaluronan synthase 1

Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide varietyof organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternatingglucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA issynthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extrudedthrough pore-like structures into the extracellular space. It serves a variety of functions, including space filling,lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during woundhealing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serumconcentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. Inaddition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes,and overexpression of HA receptors has been correlated with tumor metastasis. HAS1 is a member of the newly identifiedvertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homologyto the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and arecently described murine hyaluronan synthase. (provided by RefSeq)

Alternate Names

HA synthase 1, HAS, huHAS1, hyaluronan synthase 1, hyaluronate synthase 1, hyaluronic acid synthase 1

Gene Symbol

HAS1

Additional Hyaluronan synthase 1 Products

Product Documents for Hyaluronan synthase 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Hyaluronan synthase 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.