IA-2/PTPRN Antibody (8E3)

Novus Biologicals, part of Bio-Techne | Catalog # H00005798-M07

Novus Biologicals, part of Bio-Techne
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H00005798-M07
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 8E3

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IA-2/PTPRN Antibodies »

Product Specifications

Immunogen

PTPRN (NP_002837, 205 a.a. ~ 311 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LLQPYLFHQFGSRDGSRVSEGSPGMVSVGPLPKAEAPALFSRTASKGIFGDHPGHSYGDLPGPSPAQLFQDSGLLYLAQELPAPSRARVPRLPEQGSSSRAEDSPEG

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for IA-2/PTPRN Antibody (8E3)

Western Blot: IA-2/PTPRN Antibody (8E3) [H00005798-M07]

Western Blot: IA-2/PTPRN Antibody (8E3) [H00005798-M07]

Western Blot: IA-2/PTPRN Antibody (8E3) [H00005798-M07] - Analysis of PTPRN expression in transfected 293T cell line by PTPRN monoclonal antibody (M07), clone 8E3. Lane 1: PTPRN transfected lysate (Predicted MW: 65.01 KDa). Lane 2: Non-transfected lysate.
Western Blot: IA-2/PTPRN Antibody (8E3) [H00005798-M07]

Western Blot: IA-2/PTPRN Antibody (8E3) [H00005798-M07]

Western Blot: IA-2/PTPRN Antibody (8E3) [H00005798-M07] - Western Blot detection against PTPRN (37.4 KDa) .
ELISA: IA-2/PTPRN Antibody (8E3) [H00005798-M07]

ELISA: IA-2/PTPRN Antibody (8E3) [H00005798-M07]

ELISA: IA-2/PTPRN Antibody (8E3) [H00005798-M07] - Detection limit for recombinant GST tagged PTPRN is 0.03 ng/ml as a capture antibody.

Applications for IA-2/PTPRN Antibody (8E3)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
It has been used for ELISA and WB.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IA-2/PTPRN

PTPRN is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq]

Long Name

Islet Cell Antigen 2/Protein Tyrosine Phosphatase Receptor-type N

Alternate Names

IA2, ICA512, PTPRN, R-PTP-N

Gene Symbol

PTPRN

UniProt

NP_002837 (Human)

Additional IA-2/PTPRN Products

Product Documents for IA-2/PTPRN Antibody (8E3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IA-2/PTPRN Antibody (8E3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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