IA-2/PTPRN Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83128

Novus Biologicals, part of Bio-Techne
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NBP1-83128-25ul
NBP1-83128
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IA-2/PTPRN Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: HSYGDLPGPSPAQLFQDSGLLYLAQELPAPSRARVPRLPEQGSSSRAEDSPEGYEKEGLGDRGEKPASPAVQPDAALQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLLPKGA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IA-2/PTPRN Antibody

Immunohistochemistry-Paraffin: IA-2/PTPRN Antibody [NBP1-83128]

Immunohistochemistry-Paraffin: IA-2/PTPRN Antibody [NBP1-83128]

Immunohistochemistry-Paraffin: IA-2/PTPRN Antibody [NBP1-83128] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry: IA-2/PTPRN Antibody [NBP1-83128]

Immunohistochemistry: IA-2/PTPRN Antibody [NBP1-83128]

Immunohistochemistry: IA-2/PTPRN Antibody [NBP1-83128] - Staining of human adrenal gland shows high expression.
Immunohistochemistry-Paraffin: IA-2/PTPRN Antibody [NBP1-83128]

Immunohistochemistry-Paraffin: IA-2/PTPRN Antibody [NBP1-83128]

Immunohistochemistry-Paraffin: IA-2/PTPRN Antibody [NBP1-83128] - Staining of human adrenal gland shows strong cytoplasmic positivity in medullary cells.
View 1 more images

Applications for IA-2/PTPRN Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IA-2/PTPRN

PTPRN is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq]

Long Name

Islet Cell Antigen 2/Protein Tyrosine Phosphatase Receptor-type N

Alternate Names

IA2, ICA512, PTPRN, R-PTP-N

Gene Symbol

PTPRN

Additional IA-2/PTPRN Products

Product Documents for IA-2/PTPRN Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IA-2/PTPRN Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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