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ICA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-56426

Novus Biologicals, part of Bio-Techne
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NBP1-56426

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Synthetic peptides corresponding to ICA1(islet cell autoantigen 1, 69kDa) The peptide sequence was selected from the N terminal of ICA1. Peptide sequence SKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFS. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for ICA1 Antibody

Western Blot: ICA1 Antibody [NBP1-56426]

Western Blot: ICA1 Antibody [NBP1-56426]

Western Blot: ICA1 Antibody [NBP1-56426] - Human HepG2, Antibody Dilution: 1.0 ug/ml There is BioGPS gene expression data showing that ICA1 is expressed in HepG2.
Immunohistochemistry: ICA1 Antibody [NBP1-56426]

Immunohistochemistry: ICA1 Antibody [NBP1-56426]

Immunohistochemistry: ICA1 Antibody [NBP1-56426] - Human Liver Tissue Observed Staining: Cytoplasm in hepatocytes Primary Antibody Concentration: 1 : 100 Other Working Concentrations: 1/600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1 : 200 Magnification: 20X Exposure Tim
Western Blot: ICA1 Antibody [NBP1-56426]

Western Blot: ICA1 Antibody [NBP1-56426]

Western Blot: ICA1 Antibody [NBP1-56426] - Hela cell lysate, concentration 0.2-1 ug/ml.

Applications for ICA1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ICA1

ICA1 is a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Long Name

Islet Cell Autoantigen 1

Alternate Names

ICAp69

Gene Symbol

ICA1

UniProt

Additional ICA1 Products

Product Documents for ICA1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ICA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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