ICA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16909

Novus Biologicals, part of Bio-Techne
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NBP2-16909
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ICA1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human ICA1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rhesus Macaque.

Localization

Cytoplasm; cytosol; Golgi apparatus membrane; Peripheral membrane protein (Potential); Cytoplasmic vesicle; secretory vesicle membrane; Peripheral membrane protein (Potential); secretory vesicle; synaptic vesicle membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ICA1 Antibody

Western Blot: ICA1 Antibody [NBP2-16909]

Western Blot: ICA1 Antibody [NBP2-16909]

Western Blot: ICA1 Antibody [NBP2-16909] - Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: ICA1 Antibody [NBP2-16909]

Immunohistochemistry-Paraffin: ICA1 Antibody [NBP2-16909]

Immunohistochemistry-Paraffin: ICA1 Antibody [NBP2-16909] - Immunohistochemical analysis of paraffin-embedded A2780-CP70 xenograft, using antibody at 1:100 dilution.

Applications for ICA1 Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ICA1

This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq]

Long Name

Islet Cell Autoantigen 1

Alternate Names

ICAp69

Gene Symbol

ICA1

UniProt

Q05084 (Human)

Additional ICA1 Products

Product Documents for ICA1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ICA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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