ICEBERG Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-85088

Novus Biologicals, part of Bio-Techne
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NBP2-85088-0.1ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all ICEBERG Antibodies »

Product Summary for ICEBERG Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human ICEBERG. Peptide sequence: DEVISQEDMNKVRDENDTVMDKARVLIDLVTGKGPKSCCKFIKHLCEEDP The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for ICEBERG Antibody

Western Blot: ICEBERG Antibody [NBP2-85088]

Western Blot: ICEBERG Antibody [NBP2-85088]

Western Blot: ICEBERG Antibody [NBP2-85088] - WB Suggested Anti-CAR18 antibody Titration: 1 ug/mL. Sample Type: Human Ovary Tumor

Applications for ICEBERG Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ICEBERG

ICEBERG, also known as Caspase recruitment domain-containing protein 18, is a 90 amino acid protein that is 10 kDa, most often expressed in the heart and placenta, down-regulates the release of IL1B, and by interacting with caspase-1 and preventing its association with RIP2 inhibits the generation of IL-1-beta. This protein is being studied for its involvement in chronic lymphocytic leukemia. The ICEBERG protein has been linked to the NOD-like receptor signaling pathway where it interacts with CASP1, CARD8, CARD16, and CARD17.

Alternate Names

caspase recruitment domain family, member 18, Caspase-1 inhibitor Iceberg, ICEBERG caspase-1 inhibitor, ICEBERGcaspase recruitment domain-containing protein 18, pseudo-ICE, UNQ5804

Gene Symbol

CARD18

Additional ICEBERG Products

Product Documents for ICEBERG Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ICEBERG Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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