IgL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00003535-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IgL Antibodies »

Product Specifications

Immunogen

IGL@ (AAH89414.1, 1 a.a. - 232 a.a.) full-length human protein. MAWTPLLLPLLTFCTVSEASYDLTQPPSVSVSPGQTARITCSGDALPRKYAFWYQQKSGQAPVLVIYEDSKRPSGIPERFSGSSSGTMATLTISGAQVEDEGDYYCYSTDISGYPVFGGGTKVTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWRSHKSYSCQVTHEGSTVEKTVAPTECS

Specificity

IGL@ - immunoglobulin lambda locus,

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for IgL Antibody

Western Blot: IgL Antibody [H00003535-B01P]

Western Blot: IgL Antibody [H00003535-B01P]

Western Blot: IgL Antibody [H00003535-B01P] - Analysis of IGL@ expression in human liver.
Western Blot: IgL Antibody [H00003535-B01P]

Western Blot: IgL Antibody [H00003535-B01P]

Western Blot: IgL Antibody [H00003535-B01P] - Analysis of IGL@ expression in transfected 293T cell line by IGL@ polyclonal antibody. Lane 1: IGL@ transfected lysate(25.52 KDa). Lane 2: Non-transfected lysate.

Applications for IgL Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IgL

Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. [provided by RefSeq]

Alternate Names

ig lambda-6 chain C region, IGL, IGLC6, immunoglobulin lambda gene cluster, immunoglobulin lambda locus, Lambda Light Chain, MGC88804

Entrez Gene IDs

3535 (Human)

Gene Symbol

IGL

UniProt

AAH89414.1 (Human)

Additional IgL Products

Product Documents for IgL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IgL Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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