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IKEPP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17195

Novus Biologicals, part of Bio-Techne
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NBP3-17195-100ul
NBP3-17195-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PSTLSGHRVCQAHGEPVLGLCPLLPLFCCPPHPPDPWSLERPRFCLLSKEEGKSFGFHLQQELGRAGHVVCRVDPGTSAQRQGLQEGDRILAVNNDV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IKEPP Antibody

Immunohistochemistry-Paraffin: IKEPP Antibody [NBP3-17195]

Immunohistochemistry-Paraffin: IKEPP Antibody [NBP3-17195]

Immunohistochemistry-Paraffin: IKEPP Antibody [NBP3-17195] - Staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells.

Applications for IKEPP Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IKEPP

IKEPP, also known as PDZD3, associates with GUCY2C to act as a regulatory protein and negatively modulates the heat-stable enterotoxin-mediated activation of GUCY2C. Specifically, IKEPP regulates the amount of cGMP produced following receptor stimulation. IKEPP has also been found to stimulate SLC9A3 activity in the presence of elevated calcium ions.

Alternate Names

FLJ22756, IKEPPPDZK2, intestinal and kidney enriched PDZ protein, Intestinal and kidney-enriched PDZ protein, Na(+)/H(+) exchange regulatory cofactor NHE-RF4, Na/Pi cotransporter C-terminal-associated protein 2, NaPi-Cap2, Natrium-phosphate cotransporter IIa C-terminal-associated protein 2, NHERF4, NHERF-4, PDZ domain containing 2, PDZ domain containing 3, PDZ domain-containing protein 2, PDZ domain-containing protein 3, Sodium-hydrogen exchanger regulatory factor 4

Gene Symbol

NHERF4

Additional IKEPP Products

Product Documents for IKEPP Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IKEPP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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