IL-1 RI Antibody (RM0013-11B7) [PerCP]

Novus Biologicals, part of Bio-Techne | Catalog # NB110-85471PCP

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB110-85471AF350

Alexa Fluor 405

NB110-85471AF405

Alexa Fluor 488

NB110-85471AF488

Alexa Fluor 532

NB110-85471AF532

Alexa Fluor 594

NB110-85471AF594

Alexa Fluor 647

NB110-85471AF647

Alexa Fluor 700

NB110-85471AF700

Alexa Fluor 750

NB110-85471AF750

Allophycocyanin

NB110-85471APC

Biotin

NB110-85471B

CoraFluor 1

NB110-85471CL1

DyLight 350

NB110-85471UV

DyLight 405

NB110-85471V

DyLight 488

NB110-85471G

DyLight 550

NB110-85471R

DyLight 594

NB110-85471DL594

DyLight 650

NB110-85471C

DyLight 680

NB110-85471FR

DyLight 755

NB110-85471IR

FITC

NB110-85471F

HRP

NB110-85471H

Janelia Fluor 525

NB110-85471JF525

Janelia Fluor 549

NB110-85471JF549

Janelia Fluor 646

NB110-85471JF646

Janelia Fluor 669

NB110-85471JF669

mFluor Violet 450 SE

NB110-85471MFV450

mFluor Violet 500 SE

NB110-85471MFV500

mFluor Violet 610 SE

NB110-85471MFV610

PE

NB110-85471PE

Forumulation

Catalog #

Azide and BSA Free

NB110-85471

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

PerCP (Excitation = 490 nm, Emission = 675 nm)

Antibody Source

Monoclonal Rat IgG₂ Clone # RM0013-11B7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-1 RI Antibodies »

Product Specifications

Immunogen

Mouse IL-1 RI (extracellular domain)

Specificity

This is recognizes the extracellular domain of mouse IL1 Receptor 1 Antibody (RM0013-11B7)

Clonality

Monoclonal

Host

Rat

Isotype

IgG₂

Applications for IL-1 RI Antibody (RM0013-11B7) [PerCP]

Application

Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-1 RI

The Interleukin 1 receptor type I (IL-1R1) belongs to the IL-1 receptor family (1). IL-1R1 binds to IL-1 alpha, IL-1 beta, and interleukin-1 receptor antagonist protein (IL-1RA). IL-1RA regulates IL-1 ligand biological activity by a competitive interaction for IL-1R1. Upon IL-1 stimulation, adaptor molecule MyD88 is first recruited to the IL-1R1-IL1R accessory protein complex, followed by the recruitment of two serine-threonine kinases, IRAK4 and IRAK, and the adaptor protein TRAF6, resulting in activation of the NF-kB pathway (2-3). Stimulation of IL-1R1, leads to activation of the transcription factors NF-B, ATF, and AP-1.

Long Name

Interleukin 1 Receptor I

Alternate Names

CD121a, IL-1RI, IL1R1, IL1RI

Gene Symbol

IL1R1

Additional IL-1 RI Products

Product Documents for IL-1 RI Antibody (RM0013-11B7) [PerCP]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for IL-1 RI Antibody (RM0013-11B7) [PerCP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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