IL-10 R beta Antibody (009)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90735

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-90735-100ul
NBP2-90735-50ul
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Key Product Details

Species Reactivity

Mouse

Applications

ELISA, Sandwich ELISA Capture

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 009

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-10 R beta Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-10 R beta (Accession#: NP_032375.2; Met1-Ser222).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Applications for IL-10 R beta Antibody (009)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Sandwich ELISA Capture

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody will detect Human IL-10 R beta in ELISA pair set (Catalog: # NBP2-79605). In a sandwich ELISA, it can be used as a capture antibody when paired with (Catalog: # NBP2-90736).

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-10 R beta

IL10RB, also known as Interleukin-10 receptor subunit beta, is a 325 amino acid protein that is 37 kDa; belongs to the type II cytokine receptor family; cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29; and its co-expression with IL10RA proteins is needed for IL10-induced signal transduction. This protein is currently being studied for research on several diseases and disorders including inflammatory bowel disease 25, early onset, autosomal recessive, hepatitis b virus, inflammatory bowel disease, hepatitis b, interferon, respiratory syncytial virus bronchiolitis, graft versus host disease, ulcerative colitis crohn's disease, anaplastic large cell lymphoma, secondary hyperparathyroidism, mumps, systemic lupus erythematosus, measles, bronchiolitis, rubella, cblc, lupus erythematosus, rheumatoid arthritis, colitis, and tumors. Interactions with IL10RB have been shown to involve IL22, UCN3, IL10RA, IL28A, and IL10 in cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, toxoplasmosis, tuberculosis, antioxidant action of vitamin-C, immune response IL-22 signaling pathway, and molecular mechanisms of cancer pathway.

Long Name

Interleukin 10 Receptor beta

Alternate Names

CDw210b, CRFB4, D21S58, IL-10R2, IL-10Rb, IL10R beta, IL10RB

Gene Symbol

IL10RB

Additional IL-10 R beta Products

Product Documents for IL-10 R beta Antibody (009)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-10 R beta Antibody (009)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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