IL-11R alpha Antibody (S08-2J3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19662

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19662-100ul
NBP3-19662-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-2J3

Concentration

0.3 mg/ml

View all IL-11 R alpha Antibodies »

Product Summary for IL-11R alpha Antibody (S08-2J3)

Immunogen

A synthetic peptide of human IL-11R alpha (Uniprot # Q14626)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-11R alpha Antibody (S08-2J3)

Western Blot: IL-11R alpha Antibody (S08-2J3) [NBP3-19662]

Western Blot: IL-11R alpha Antibody (S08-2J3) [NBP3-19662]

Western Blot: IL-11R alpha Antibody (S08-2J3) [NBP3-19662] - Western blot detection of IL-11R alpha in K562 cell lysates using NBP3-19662 (1:1000 diluted). Predicted band size: 45kDa. Observed band size: 45kDa.
Immunohistochemistry-Paraffin: IL-11R alpha Antibody (S08-2J3) [NBP3-19662]

Immunohistochemistry-Paraffin: IL-11R alpha Antibody (S08-2J3) [NBP3-19662]

Immunohistochemistry-Paraffin: IL-11R alpha Antibody (S08-2J3) [NBP3-19662] - Immunohistochemistry of IL-11R alpha in paraffin-embedded Human colon cancer tissue using NBP3-19662 at dilution 1/50

Applications for IL-11R alpha Antibody (S08-2J3)

Application
Recommended Usage

Immunohistochemistry

1/100

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-11 R alpha

IL-11 Ra (Interleukin-11 receptor alpha) is a widely expressed transmembrane protein that associates with gp130 to form a functional receptor complex for the cytokine IL-11. gp130 also functions as a subunit in the receptors for Cardiotrophin-1, CNTF, IL-6, IL-27, IL-31, LIF, and Oncostatin M. IL-11 Ra plays a role in female reproduction and the survival of oligodendrocytes and colonic epithelial cells. It enhances osteoclast differentiation and bone remodeling but inhibits adipocyte differentiation. Soluble IL-11 Ra confers IL-11 responsiveness to cells expressing gp130, while in cells expressing transmembrane IL-11 Ra and gp130, soluble IL-11 Ra acts as an IL-11 antagonist.

Long Name

Interleukin 11 Receptor alpha

Alternate Names

IL-11Ra, IL11R alpha, IL11RA

Gene Symbol

IL11RA

Additional IL-11 R alpha Products

Product Documents for IL-11R alpha Antibody (S08-2J3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-11R alpha Antibody (S08-2J3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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