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IL-13R alpha 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16942

Novus Biologicals, part of Bio-Techne
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NBP2-16942

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for IL-13R alpha 1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human IL-13R alpha 1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Porcine (80%), Bovine (84%), Mouse (72%).

Localization

Membrane; Single-pass type I membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-13R alpha 1 Antibody

Western Blot: IL-13R alpha 1 Antibody [NBP2-16942]

Western Blot: IL-13R alpha 1 Antibody [NBP2-16942]

Western Blot: IL-13R alpha 1 Antibody [NBP2-16942] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with IL13 Receptor alpha 1 antibody diluted at 1:20000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunohistochemistry-Paraffin: IL-13R alpha 1 Antibody [NBP2-16942]

Immunohistochemistry-Paraffin: IL-13R alpha 1 Antibody [NBP2-16942]

Immunohistochemistry-Paraffin: IL-13 R alpha 1 Antibody [NBP2-16942] - Analysis of paraffin-embedded Hepatoma, using antibody at 1:500 dilution.
Western Blot: IL-13R alpha 1 Antibody [NBP2-16942]

Western Blot: IL-13R alpha 1 Antibody [NBP2-16942]

Western Blot: IL-13R alpha 1 Antibody [NBP2-16942] - U87-MG whole cell and membrane extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with IL13 Receptor NBP2-19301) was used to detect the primary antibody.

Applications for IL-13R alpha 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:5000-1:20000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IL-13 R alpha 1

The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq]

Long Name

Interleukin 13 Receptor alpha 1

Alternate Names

CD213a1, IL-13Ra1, IL13R alpha 1, IL13RA1

Gene Symbol

IL13RA1

UniProt

Additional IL-13 R alpha 1 Products

Product Documents for IL-13R alpha 1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-13R alpha 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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