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IL-18 R beta/IL-1 R7/ACPL Antibody (B-B46) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14574

Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-14574-200ul
NBP3-14574-500ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Functional

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # B-B46

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Summary for IL-18 R beta/IL-1 R7/ACPL Antibody (B-B46) - Azide and BSA Free

Immunogen

Recombinant human IL-18 R beta/IL-1 R7/ACPL

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Stable at 4C for 12 months.

Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells

Applications for IL-18 R beta/IL-1 R7/ACPL Antibody (B-B46) - Azide and BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Biological Activity: Inhibits human IFN-gamma secretion induced by IL-18 stimulated cells
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS. Sterile-filtered through 0.22 um.

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-18 R beta/IL-1 R7

ACPL is encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.

Long Name

Interleukin 18 Receptor beta

Alternate Names

AcPL, CD218b, IL-1 R7, IL-18Rb, IL18R beta, IL18RAP

Gene Symbol

IL18RAP

Additional IL-18 R beta/IL-1 R7 Products

Product Documents for IL-18 R beta/IL-1 R7/ACPL Antibody (B-B46) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-18 R beta/IL-1 R7/ACPL Antibody (B-B46) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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