IL-20 R beta/FNDC6 Antibody (20RNTC) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-00466

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # 20RNTC

Format

BSA Free

Concentration

0.5 mg/ml

View all IL-20 R beta Antibodies »

Product Specifications

Immunogen

The immunogen for this antibody is FNDC6 (IL-20R2).

Reactivity Notes

Human, Mouse

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Scientific Data Images for IL-20 R beta/FNDC6 Antibody (20RNTC) - BSA Free

Immunocytochemistry/ Immunofluorescence: IL-20 R beta/FNDC6 Antibody (20RNTC) - BSA Free [NBP2-00466]

Immunocytochemistry/ Immunofluorescence: IL-20 R beta/FNDC6 Antibody (20RNTC) - BSA Free [NBP2-00466]

Immunocytochemistry/Immunofluorescence: FNDC6 Antibody (20RNTC) [NBP2-00466] - Immunofluorescent microscopy of fixed and permeabilized A375 cells using 10 ug/ml of Anti-Human/Mouse IL-20 Receptor 2 (IL-20Rb) Purified (right) or Rat IgG2a kappa Isotype Control Purified (NBP1-43321) (left) followed by Anti-Rat IgG Biotin and then Streptavidin FITC.

Applications for IL-20 R beta/FNDC6 Antibody (20RNTC) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-10 ug/ml

Immunocytochemistry/ Immunofluorescence

1-10 ug/ml
Application Notes
This 20RNTC antibody has been tested by immunofluorescent staining and flow cytometric analysis of fixed and permeabilized A375 cells. This 20RNTC antibody has also been reported for use in immunocytochemistry and immunoblotting.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS (pH 7.2)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: IL-20 R beta

This 20RNTC monoclonal antibody recognizes mouse and human IL-20R2 (interleukin-20 receptor 2, IL-20Rb) in either of its two heterodimeric complexes formed by pairing with IL-20R1 or IL-22R1. IL-20R2 belongs to the class II cytokine receptor family that shares a characteristic pattern of cysteine, proline and tryptophan residues in the extracellular domain. IL-20R2 paired with IL-20R1 forms a receptor that binds IL-20, IL-19, or IL-24. IL-20R2 paired with IL22R1 forms a receptor that binds IL-20 or IL-24. The IL-20R complex signals primarily via the JAK-STAT pathway. IL-20R2 is found predominantly on cells of epithelial origin such as gut and skin and can be upregulated during inflammation. Immunofluorescent staining of A375 cells reveals a punctate staining pattern at the cell membrane, as well as diffuse, cytoplasmic staining that is likely associated with protein synthesis and transport in the endoplasmic reticulum and golgi.

Long Name

Interleukin 20 Receptor beta

Alternate Names

DIRS1, FNDC6, IL-20R2, IL-20Rb, IL20R beta, IL20RB

Gene Symbol

IL20RB

Additional IL-20 R beta Products

Product Documents for IL-20 R beta/FNDC6 Antibody (20RNTC) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-20 R beta/FNDC6 Antibody (20RNTC) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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