IL-21 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11321

Novus Biologicals, part of Bio-Techne
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NBP3-11321
NBP3-11321-0.025mg
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Key Product Details

Species Reactivity

Rabbit

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Chicken IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-21 Antibodies »

Product Specifications

Immunogen

Recombinant rabbit IL-21

Clonality

Polyclonal

Host

Chicken

Isotype

IgG

Scientific Data Images for IL-21 Antibody

ELISA: IL-21 Antibody [NBP3-11321]

ELISA: IL-21 Antibody [NBP3-11321]

ELISA: IL-21 Antibody [NBP3-11321] - Recombinant Rabbit IL-21 detected using Chicken anti Rabbit IL-21 (AHP2826) as the capture reagent and Chicken anti Rabbit IL-21:Biotin as the detection reagent followed by Streptavidin:HRP.

Applications for IL-21 Antibody

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: IL-21

IL-21 (Interleukin-21) is member of the family of cytokines that utilize the common gamma chain as a receptor subunit. This subunit is also a component of the receptors for IL-2, IL-4, IL-7, IL-9, and IL-15. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex of the common gamma chain and the IL-21-specific IL-21 R. IL-21 supports Tfh cell development, immunoglobulin affinity maturation, plasma cell differentiation, B cell memory responses, and the migration of dendritic cells to draining lymph nodes. It costimulates the activation, proliferation, and survival of CD8+ T cells and NKT cells and promotes Th17 cell polarization. It blocks the generation of regulatory T cells and their suppressive effects on CD4+ T cells. In addition, IL-21 suppresses cutaneous hypersensitivity reactions by limiting allergen-specific IgE production and mast cell degranulation.

Long Name

Interleukin 21

Alternate Names

CVID11, IL21, Za11

Gene Symbol

IL21

UniProt

G1T948 (Rabbit)

Additional IL-21 Products

Product Documents for IL-21 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IL-21 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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