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Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Intracellular Staining by Flow Cytometry

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 875504

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human IL-22BP
Thr22-Pro263
Accession # Q969J5

Specificity

Detects human IL-22BP in direct ELISAs. In direct ELISAs, no cross-reactivity with mouse IL-22BP is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for IL-22BP/IL22 RA2 Antibody (875504) [DyLight 405]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Intracellular Staining by Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-22BP

The protein encoded by the IL22 RA2 gene is a soluble class II cytokine receptor. This protein has been shown to specificallybind to interleukin 22 (IL22), block the interaction of IL22 with its cell surface receptor, and thus inhibit IL22activity. This protein functions as an IL22 antagonist, and may be important in the regulation of inflammatoryresponse. Three alternatively spliced transcript variants encoding distinct isoforms have been described. (provided byRefSeq)

Long Name

Interleukin 22 Binding Protein

Alternate Names

CRF2-10, CRF2-X, IL-22 RA2, IL22BP, IL22RA2

Gene Symbol

IL22RA2

Additional IL-22BP Products

Product Documents for IL-22BP/IL22 RA2 Antibody (875504) [DyLight 405]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-22BP/IL22 RA2 Antibody (875504) [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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