IL-24 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56407

Novus Biologicals, part of Bio-Techne
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NB100-56407
NB100-56407SS
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Key Product Details

Species Reactivity

Human, Primate

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all IL-24 Antibodies »

Product Specifications

Immunogen

Amino acids 123-136 (KNYHNRTVEVRTLK) of human IL-24 were used as the immunogen for this antibody.

Specificity

The amino acid sequence used as immunogen is found in many of the IL-24 isoforms, including isoforms of 219, 207, 206, 154, 143 and 120 amino acids.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL-24 Antibody

Western Blot: IL-24 Antibody [NB100-56407]

Western Blot: IL-24 Antibody [NB100-56407]

Western Blot: IL-24 Antibody [NB100-56407] - Analysis of IL-24 in the A) absence and B) presence of blocking peptide in Jurkat cell lysate using this antibody at 0.5 ug/ml. Goat anti-rabbit IgG HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Flow Cytometry: IL-24 Antibody [NB100-56407]

Flow Cytometry: IL-24 Antibody [NB100-56407]

Flow Cytometry: IL-24 Antibody [NB100-56407] - Cell surface flow cytometry analysis of IL-24 in Jurkat cells using this antibody at 5 ug/10^6 cells. The shaded histogram represents cells only, green represents isotype control antibody, and red represents this antibody.

Applications for IL-24 Antibody

Application
Recommended Usage

Flow Cytometry

2-5 ug/10^6 cells

Western Blot

0.5-3 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.2% gelatin

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-24

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radio sensitization in malignant gliomas in a p53-independent manner.

Long Name

Interleukin 24

Alternate Names

C49A, FISP, IL24, MDA-7, MOB-5, ST16

Entrez Gene IDs

11009 (Human)

Gene Symbol

IL24

Additional IL-24 Products

Product Documents for IL-24 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-24 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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