Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.

Long Name

Interleukin 29

Alternate Names

IFN-lambda 1, IL29

Gene Symbol

IFNL1

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Product Specific Notices for IL-29/IFN-lambda 1 Antibody (B-Z29) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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IL-29/IFN-lambda 1 Antibody (B-Z29) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18107

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Product Summary for IL-29/IFN-lambda 1 Antibody (B-Z29) - Azide and BSA Free

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Background: IL-29/IFN-lambda 1