Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.

Long Name

Interleukin 29

Alternate Names

IFN-lambda 1, IL29

Gene Symbol

IFNL1

Additional IL-29/IFN-lambda 1 Products

Product Documents for IL-29/IFN-lambda 1 Antibody [DyLight 350]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for IL-29/IFN-lambda 1 Antibody [DyLight 350]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

IL-29/IFN-lambda 1 Antibody [DyLight 350]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-99978UV

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all IL-29/IFN-lambda 1 Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Applications for IL-29/IFN-lambda 1 Antibody [DyLight 350]

ELISA

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: IL-29/IFN-lambda 1