IL-37/IL-1F7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33712

Novus Biologicals, part of Bio-Techne
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NBP2-33712
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IL-37/IL-1F7 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL-37/IL-1F7 Antibody

Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-33712]

Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-33712]

Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-33712] - Staining of human rectum shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-33712]

Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-33712]

Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-33712] - Staining of human testis shows strong granular cytoplasmic positivity in cells in seminiferus ducts.
Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-33712]

Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-33712]

Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-33712] - Staining of human skin shows moderate cytoplasmic positivity in keratinocytes in stratum granulosum.
View 1 more images

Applications for IL-37/IL-1F7 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-37/IL-1F7

IL1F7 is encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.

Long Name

Interleukin 37

Alternate Names

FIL1 zeta, IL-1F7, IL37

Gene Symbol

IL37

UniProt

Q9NZH6 (Human)

Additional IL-37/IL-1F7 Products

Product Documents for IL-37/IL-1F7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-37/IL-1F7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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