IL-4I1 Antibody (C2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41670

Novus Biologicals, part of Bio-Techne
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NBP3-41670
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Key Product Details

Species Reactivity

Human, Porcine

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # C2

Concentration

1 mg/ml

View all IL-4I1 Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human IL-4I1 (Uniprot#: Q96RQ9; Met1-Glu245 (Uniprot#: Q96RQ9)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for IL-4I1 Antibody (C2)

IL-4I1 Antibody (C2)

Immunohistochemistry-Paraffin: IL-4I1 Antibody (C2) [NBP3-41670] -

Immunohistochemistry-Paraffin: IL-4I1 Antibody (C2) [NBP3-41670] - DAB staining on IHC-P; Sample: Human Lymph node Tissue; Primary Ab: 20ug/ml NBP3-41670; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

Applications for IL-4I1 Antibody (C2)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-4I1

Interleukin 4 induced protein 1 (IL-4I1), also known as protein FIG-1 and L-amino acid oxidase, is encoded by a B-cell IL-4-inducible gene, FIG1, and is highly expressed in primary metastinal B-cell lymphomas. It belongs to the flavin monoamine oxidase family, FIG1 subfamily. Enzymological characterization reveals that IL-4I1 has L-amino acid oxidase activity with preference toward aromatic amino acids. Studies have shown that hIL-4I1 inhibited the proliferation of CD3-stimulated T lymphocytes with a similar effect on CD4(+) and CD8(+) T cells. Its inhibitory effect was dependent on enzymatic activity and H2O2 production. Its restricted expression to lymphoid tissues indicates that it may play an important function in the immune system.

Long Name

Interleukin 4-induced Protein-1

Alternate Names

FIG1, IL4I1

Gene Symbol

IL4I1

Additional IL-4I1 Products

Product Documents for IL-4I1 Antibody (C2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-4I1 Antibody (C2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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