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IL-4I1 Antibody (CL9071)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-88929

Novus Biologicals, part of Bio-Techne
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NBP2-88929

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL9071

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a synthetic peptide corresponding to amino acids: SFRRPFWREEHIEGGHSNTDRPSR

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for IL-4I1 Antibody (CL9071)

Immunohistochemistry-Paraffin: IL-4I1 Antibody (CL9071) [NBP2-88929]

Immunohistochemistry-Paraffin: IL-4I1 Antibody (CL9071) [NBP2-88929]

Immunohistochemistry-Paraffin: IL-4I1 Antibody (CL9071) [NBP2-88929] - Analysis in human testis and skeletal muscle tissues using NBP2-88929 antibody. Corresponding IL4I1 RNA-seq data are presented for the same tissues.
Western Blot: IL-4I1 Antibody (CL9071) [NBP2-88929]

Western Blot: IL-4I1 Antibody (CL9071) [NBP2-88929]

Western Blot: IL-4I1 Antibody (CL9071) [NBP2-88929] - Analysis in human cell line HDLM-2.
Immunohistochemistry-Paraffin: IL-4I1 Antibody (CL9071) [NBP2-88929]

Immunohistochemistry-Paraffin: IL-4I1 Antibody (CL9071) [NBP2-88929]

Immunohistochemistry-Paraffin: IL-4I1 Antibody (CL9071) [NBP2-88929] - Staining of human kidney shows no positivity in cells in glomeruli.

Applications for IL-4I1 Antibody (CL9071)

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-4I1

Interleukin 4 induced protein 1 (IL-4I1), also known as protein FIG-1 and L-amino acid oxidase, is encoded by a B-cell IL-4-inducible gene, FIG1, and is highly expressed in primary metastinal B-cell lymphomas. It belongs to the flavin monoamine oxidase family, FIG1 subfamily. Enzymological characterization reveals that IL-4I1 has L-amino acid oxidase activity with preference toward aromatic amino acids. Studies have shown that hIL-4I1 inhibited the proliferation of CD3-stimulated T lymphocytes with a similar effect on CD4(+) and CD8(+) T cells. Its inhibitory effect was dependent on enzymatic activity and H2O2 production. Its restricted expression to lymphoid tissues indicates that it may play an important function in the immune system.

Long Name

Interleukin 4-induced Protein-1

Alternate Names

FIG1, IL4I1

Gene Symbol

IL4I1

Additional IL-4I1 Products

Product Documents for IL-4I1 Antibody (CL9071)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-4I1 Antibody (CL9071)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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