Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2F4

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all IL6R Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human IL6R(NP_000556) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

49.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL6R Antibody (OTI2F4) - Azide and BSA Free

Western Blot: IL6R Antibody (OTI2F4)Azide and BSA Free [NBP2-71029]

Western Blot: IL6R Antibody (OTI2F4)Azide and BSA Free [NBP2-71029]

Western Blot: IL6R Antibody (OTI2F4) - Azide and BSA Free [NBP2-71029] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL6R.
Immunocytochemistry/ Immunofluorescence: IL6R Antibody (OTI2F4) - Azide and BSA Free [NBP2-71029]

Immunocytochemistry/ Immunofluorescence: IL6R Antibody (OTI2F4) - Azide and BSA Free [NBP2-71029]

Immunocytochemistry/Immunofluorescence: IL6R Antibody (OTI2F4) - Azide and BSA Free [NBP2-71029] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY IL6R.
Immunohistochemistry: IL6R Antibody (OTI2F4) - Azide and BSA Free [NBP2-71029]

Immunohistochemistry: IL6R Antibody (OTI2F4) - Azide and BSA Free [NBP2-71029]

Immunohistochemistry: IL6R Antibody (OTI2F4) - Azide and BSA Free [NBP2-71029] - Analysis of Human lymph node tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Applications for IL6R Antibody (OTI2F4) - Azide and BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:150

Western Blot

1:4000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Reconstitution

we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process.

Formulation

Lyophilized from PBS (pH 7.3) with 8% Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IL6R

Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Alternate Names

CD126, CD126 antigen, gp80, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-1, IL6RA, IL-6RA, IL-6R-alpha, interleukin 6 receptor, interleukin 6 receptor alpha subunit, interleukin-6 receptor subunit alpha, Membrane glycoprotein 80, MGC104991

Gene Symbol

IL6R

Additional IL6R Products

Product Documents for IL6R Antibody (OTI2F4) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IL6R Antibody (OTI2F4) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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