ILVBL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-78433

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ICC/IF (Negative), Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.20 mg/ml

View all ILVBL Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to an internal portion of the human ILVBL protein (between residues 350-500) [UniProt A1L0T0]

Localization

Membrane; Single-pass membrane protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ILVBL Antibody

Western Blot: ILVBL Antibody [NBP1-78433]

Western Blot: ILVBL Antibody [NBP1-78433]

Western Blot: ILVBL Antibody [NBP1-78433] - Analysis of IVLBL in overexpression lysate.
Western Blot: ILVBL Antibody [NBP1-78433]

Western Blot: ILVBL Antibody [NBP1-78433]

Western Blot: ILVBL Antibody [NBP1-78433] - Analysis of ILVBL in human kidney tissue lysate.

Applications for ILVBL Antibody

Application
Recommended Usage

Western Blot

1:1000
Application Notes
This ILVBL antibody is useful for Western Blot, where a band is seen ~67 kDa in human kidney tissue lysate and ILVBL overexpression lysates.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS and 30% Glycerol

Preservative

0.05% Sodium Azide

Concentration

0.20 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ILVBL

ILVBL (IHAS) is a ubiquitiously expressed 68 kDa membrane protein which belongs to a family of thiamine pyrophosate-binding proteins. While ILVB is known to be involved in the initial steps of branched chain amino acid synthesis, the exact role of this protein in mammals is not known. However, the gene does show similarity to the acetolactate synthase enzyme found in bacteria. Recently investigators mapped the ILVBL gene to the 19p13.1 chromosome. This region coincides with the CADASIL critical region, which is an autosomal dominant condition that results in infarcts of the subcortical regions of the brain leading to dementia. However, there were no mutations in this gene of CADISIL patients, so its role, if any, is not known (PMID:8954801).

Alternate Names

acetolactate synthase homolog, acetolactate synthase-like protein, AHASFLJ39061,209L8, EC 2.2.1, EC 2.2.1.-, ILV2H, ilvB (bacterial acetolactate synthase)-like, IlvB-like protein, MGC1269, MGC19535

Entrez Gene IDs

10994 (Human)

Gene Symbol

ILVBL

UniProt

A1L0T0 (Human)

Additional ILVBL Products

Product Documents for ILVBL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ILVBL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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