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IMMP2L Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81591

Novus Biologicals, part of Bio-Techne
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NBP1-81591
NBP1-81591-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NRYVKVPRGHIWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLESVLPPERLPVQREEE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IMMP2L Antibody

Immunocytochemistry/ Immunofluorescence: IMMP2L Antibody [NBP1-81591]

Immunocytochemistry/ Immunofluorescence: IMMP2L Antibody [NBP1-81591]

Immunocytochemistry/Immunofluorescence: IMMP2L Antibody [NBP1-81591] - Immunofluorescent staining of human cell line U-251 MG shows localization to mitochondria.
Immunohistochemistry: IMMP2L Antibody [NBP1-81591]

Immunohistochemistry: IMMP2L Antibody [NBP1-81591]

Immunohistochemistry: IMMP2L Antibody [NBP1-81591] - Staining of human parathyroid gland shows strong cytoplasmic positivity in glandular cells.

Applications for IMMP2L Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IMMP2L

IMMP2L is a gene that codes for a protein whose function is to catalyze the removal of transit peptides that are required in order to target protein from the mitochondrial matrix into the inter-membrane space in all tissues except the liver and lung. IMMP2L has a length of 175 amino acids and a weight of approximately 20 kDa, and it has a shorter isoform comprised of 110 amino acids with a weight of approximately 12 kDa. Current studies are being done on diseases and disorders related to this gene including Tourette syndrome and malaria. IMMP2L has also been shown to have interactions with ALDH1B1, GPX4, GUF1, HACL1, and IDO2 in pathways such as the protein export pathway.

Alternate Names

EC 3.4.21, EC 3.4.21.-, IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae), IMP2 inner mitochondrial membrane protease-like (S. cerevisiae), IMP2inner mitochondrial membrane peptidase 2 like, IMP2-LIKE, IMP2-like protein, mitochondrial inner membrane protease subunit 2

Gene Symbol

IMMP2L

Additional IMMP2L Products

Product Documents for IMMP2L Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IMMP2L Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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