IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16786

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16786-100ul
NBP3-16786-20ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4X3S10

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IMP Dehydrogenase 2/IMPDH2 Antibodies »

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human IMP Dehydrogenase 2/IMPDH2 (P12268). QANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10)

Western Blot: IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10) [NBP3-16786]

Western Blot: IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10) [NBP3-16786]

Western Blot: IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10) [NBP3-16786] - Western blot analysis of extracts of various cell lines, using IMP Dehydrogenase 2/IMPDH2 Rabbit mAb (NBP3-16786) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Immunocytochemistry/ Immunofluorescence: IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10) [NBP3-16786]

Immunocytochemistry/ Immunofluorescence: IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10) [NBP3-16786]

Immunocytochemistry/Immunofluorescence: IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10) [NBP3-16786] - Immunofluorescence analysis of U-2 OS cells using IMP Dehydrogenase 2/IMPDH2 Rabbit mAb (NBP3-16786) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunocytochemistry/ Immunofluorescence: IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10) [NBP3-16786]

Immunocytochemistry/ Immunofluorescence: IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10) [NBP3-16786]

Immunocytochemistry/Immunofluorescence: IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10) [NBP3-16786] - Immunofluorescence analysis of C6 cells using IMP Dehydrogenase 2/IMPDH2 Rabbit mAb (NBP3-16786) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Applications for IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:200

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IMP Dehydrogenase 2/IMPDH2

IMPDH2 encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Long Name

Inosine 5'-Monophosphate Dehydrogenase 2

Alternate Names

IMDH2, IMP Oxireductase 2, IMPD2, IMPDH2

Gene Symbol

IMPDH2

Additional IMP Dehydrogenase 2/IMPDH2 Products

Product Documents for IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IMP Dehydrogenase 2/IMPDH2 Antibody (4X3S10)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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