IMP5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24916

Novus Biologicals, part of Bio-Techne
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NBP3-24916
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IMP5 Antibodies »

Product Summary for IMP5 Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein IMP5 using the following amino acid sequence: HTKGWLAQGQGAHGLLIVSRVSDQQCSDTTLAPQDPRQPLADLTIPVAMLHYADMLDILSHTRGEAVVRVAMYAPPEPIID

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IMP5 Antibody

IMP5 Antibody Immunohistochemistry-Paraffin: IMP5 Antibody [NBP3-24916]

Immunohistochemistry-Paraffin: IMP5 Antibody [NBP3-24916]

Staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts.

Applications for IMP5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IMP5

IMP5 is a protein that functions as an intramembrane-cleaving aspartic protease, and may have the ability to cleave type II membrance signal peptides in the membrane's hydrophobic plane, and is encoded by a gene made up of 684 amino acids and a mass of approximately 74.5 kDa. Current studies are being done on several diseases and disorders relating to this protein, including suprenuclear palsy, Parkinson's disease, and malaria. IMP5 has also been shown to have interactions with BAP1, TAF1D, and DTNBP1.

Alternate Names

EC 3.4.23, EC 3.4.23.-, IMP-5, intramembrane protease 5, signal peptide peptidase-like 2C, SPPL2c, SPP-like 2C

Gene Symbol

SPPL2C

Additional IMP5 Products

Product Documents for IMP5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IMP5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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