Importin alpha 3/KPNA4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38541

Novus Biologicals, part of Bio-Techne
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NBP2-38541
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Importin alpha 3/KPNA4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: KRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Importin alpha 3/KPNA4 Antibody

Western Blot: Importin alpha 3/KPNA4 Antibody [NBP2-38541]

Western Blot: Importin alpha 3/KPNA4 Antibody [NBP2-38541]

Western Blot: Importin alpha 3/KPNA4 Antibody [NBP2-38541] - Analysis using Anti-KPNA4 antibody NBP2-38541 (A) shows similar pattern to independent antibody NBP2-14173 (B).
Immunocytochemistry/ Immunofluorescence: Importin alpha 3/KPNA4 Antibody [NBP2-38541]

Immunocytochemistry/ Immunofluorescence: Importin alpha 3/KPNA4 Antibody [NBP2-38541]

Immunocytochemistry/Immunofluorescence: Importin alpha 3/KPNA4 Antibody [NBP2-38541] - Immunofluorescent staining of human cell line A-431 shows localization to nucleus & nuclear membrane.
Immunohistochemistry-Paraffin: Importin alpha 3/KPNA4 Antibody [NBP2-38541]

Immunohistochemistry-Paraffin: Importin alpha 3/KPNA4 Antibody [NBP2-38541]

Immunohistochemistry-Paraffin: Importin alpha 3/KPNA4 Antibody [NBP2-38541] - Staining of human testis shows strong nuclear and cytoplasmic positivity in cells of seminiferus ducts.

Applications for Importin alpha 3/KPNA4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Importin alpha 3/KPNA4

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Long Name

Karyopherin alpha 4

Alternate Names

KPNA4, QIP12, SRP3

Gene Symbol

KPNA4

UniProt

O00629

Additional Importin alpha 3/KPNA4 Products

Product Documents for Importin alpha 3/KPNA4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Importin alpha 3/KPNA4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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