Importin alpha 5/KPNA1/SRP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1370

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Importin alpha 5/KPNA1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence TTPGKENFRLKSY-C corresponding to N-Terminus according to NP_002255.3.

Localization

Cytoplasmic

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Importin alpha 5/KPNA1/SRP1 Antibody

Western Blot: Importin alpha 5/KPNA1/SRP1 Antibody [NB100-1370]

Western Blot: Importin alpha 5/KPNA1/SRP1 Antibody [NB100-1370]

Western Blot: Importin alpha 5/KPNA1/SRP1 Antibody [NB100-1370] - HeLa lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Applications for Importin alpha 5/KPNA1/SRP1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 60 kDa band observed in lysates of HEK293, HeLa and HEPG2 (calculated MW of 60.3 kDa band according to NP_002255.1).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Importin alpha 5/KPNA1

Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The KPNA1 product interacts with RAG1 and may play a role in V(D)J recombination.

Alternate Names

IPOA5, KPNA1, NPI-1, RCH2, SRP1

Entrez Gene IDs

3836 (Human); 16646 (Mouse); 288064 (Rat)

Gene Symbol

KPNA1

UniProt

NP_002255. (Human)

Additional Importin alpha 5/KPNA1 Products

Product Documents for Importin alpha 5/KPNA1/SRP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Importin alpha 5/KPNA1/SRP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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