Importin alpha 5/KPNA1/SRP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76297

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Importin alpha 5/KPNA1 Antibodies »

Product Summary for Importin alpha 5/KPNA1/SRP1 Antibody - BSA Free

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA1. The immunogen is located within amino acids 30 - 80 of KPNA1. Amino Acid Squence: NVATAEEETEEEVMS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Importin alpha 5/KPNA1/SRP1 Antibody - BSA Free

Western Blot: Importin alpha 5/KPNA1/SRP1 AntibodyBSA Free [NBP1-76297]

Western Blot: Importin alpha 5/KPNA1/SRP1 AntibodyBSA Free [NBP1-76297]

Western Blot: Importin alpha 5/KPNA1/SRP1 Antibody [NBP1-76297] - Hela cell lysate with KPNA1 antibody at 1ug/mL.
Immunocytochemistry/ Immunofluorescence: Importin alpha 5/KPNA1/SRP1 Antibody - BSA Free [NBP1-76297]

Immunocytochemistry/ Immunofluorescence: Importin alpha 5/KPNA1/SRP1 Antibody - BSA Free [NBP1-76297]

Immunocytochemistry/Immunofluorescence: Importin alpha 5/KPNA1/SRP1 Antibody [NBP1-76297] - Immunofluorescence of KPNA1 in K562 cells with KPNA1 antibody at 20 ug/mL.
Immunocytochemistry/ Immunofluorescence: Importin alpha 5/KPNA1/SRP1 Antibody - BSA Free [NBP1-76297]

Immunocytochemistry/ Immunofluorescence: Importin alpha 5/KPNA1/SRP1 Antibody - BSA Free [NBP1-76297]

Immunocytochemistry/Immunofluorescence: Importin alpha 5/KPNA1/SRP1 Antibody [NBP1-76297] - Immunocytochemistry of KPNA1 in HeLa cells with KPNA1 antibody at 2.5 ug/mL.

Applications for Importin alpha 5/KPNA1/SRP1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2.5-20 ug/ml

Western Blot

1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Importin alpha 5/KPNA1

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA1, also known as importin alpha 5, is the alpha subunit of karyopherin, which forms a complex with importin subunit beta-1 and functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. It is ubiquitously expressed and polyubiquitinated in the presence of RAG1. KPNA1 interacts with various virus nucleoproteins, including those of Ebola and influenza.

Alternate Names

IPOA5, KPNA1, NPI-1, RCH2, SRP1

Gene Symbol

KPNA1

UniProt

NP_002255 (Human)

Additional Importin alpha 5/KPNA1 Products

Product Documents for Importin alpha 5/KPNA1/SRP1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Importin alpha 5/KPNA1/SRP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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