Inhibin beta A Antibody (C3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41220

Novus Biologicals, part of Bio-Techne
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NBP3-41220
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # C3

Concentration

1 mg/ml

View all INHBA Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human Inhibin beta A (Uniprot#: P08476; Gly311-Ser426 (Uniprot#: P08476)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Inhibin beta A Antibody (C3)

Inhibin beta A Antibody (C3)

Immunohistochemistry-Paraffin: Inhibin beta A Antibody (C3) [NBP3-41220] -

Immunohistochemistry-Paraffin: Inhibin beta A Antibody (C3) [NBP3-41220] - DAB staining on IHC-P; Sample: Human Small intestine Tissue; Primary Ab: 20ug/ml NBP3-41220; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

Applications for Inhibin beta A Antibody (C3)

Application
Recommended Usage

Immunohistochemistry

5-20ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: INHBA

The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Long Name

Inhibin Subunit Beta A

Alternate Names

Activin Beta A, Inhibin Beta A, Inhibin Subunit Beta A

Gene Symbol

INHBA

Additional INHBA Products

Product Documents for Inhibin beta A Antibody (C3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Inhibin beta A Antibody (C3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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