Inhibin beta A Antibody (SR4080)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27818

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27818-100ul
NBP3-27818-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR4080

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all INHBA Antibodies »

Product Summary for Inhibin beta A Antibody (SR4080)

Immunogen

A synthesized peptide derived from human Inhibin beta A (Uniprot #: P08476)

Specificity

Detects endogenous levels of total Inhibin beta A

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Inhibin beta A Antibody (SR4080)

Western Blot: Inhibin beta A Antibody (SR4080) [NBP3-27818] -

Western Blot: Inhibin beta A Antibody (SR4080) [NBP3-27818] - Western blot analysis of Inhibin beta A expression in Human fetal brain lysate.

Applications for Inhibin beta A Antibody (SR4080)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: INHBA

The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Long Name

Inhibin Subunit Beta A

Alternate Names

Activin Beta A, Inhibin Beta A, Inhibin Subunit Beta A

Gene Symbol

INHBA

Additional INHBA Products

Product Documents for Inhibin beta A Antibody (SR4080)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Inhibin beta A Antibody (SR4080)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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