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INPP5B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31705

Novus Biologicals, part of Bio-Techne
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NBP1-31705

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human INPP5B. The exact sequence is proprietary.

Reactivity Notes

Mouse (87%), Rat (87%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

113 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for INPP5B Antibody

Western Blot: INPP5B Antibody [NBP1-31705]

Western Blot: INPP5B Antibody [NBP1-31705]

Western Blot: INPP5B Antibody [NBP1-31705] - Sample (30 ug of whole cell lysate) A: H1299 7. 5% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: INPP5B Antibody [NBP1-31705]

Immunohistochemistry-Paraffin: INPP5B Antibody [NBP1-31705]

Immunohistochemistry-Paraffin: INPP5B Antibody [NBP1-31705] - Paraffin-embedded Ca922 xenograft, using antibody at 1:100 dilution.

Applications for INPP5B Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: INPP5B

Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]

Alternate Names

75kD, EC 3.1.3, inositol polyphosphate-5-phosphatase, 75kDa, MGC65156, MGC71303,5PTase, Phosphoinositide 5-phosphatase

Gene Symbol

INPP5B

Additional INPP5B Products

Product Documents for INPP5B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for INPP5B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.