INSL3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-04435

Novus Biologicals, part of Bio-Techne
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NBP3-04435-100ul
NBP3-04435-20ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all INSL3 Antibodies »

Product Summary for INSL3 Antibody - BSA Free

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human INSL3 (NP_005534.2). MDPRLPAWALVLLGPALVFALGPAPTPEMREKLCGHHFVRALVRVCGGPRWSTEARRPATGGDRELLQWLERRHLLHGLVADSNLTLGPGLQPLPQTSHHHRHHRAAATNPARYCCLSGCTQQDLLTLCPY

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for INSL3 Antibody - BSA Free

Immunohistochemistry-Paraffin: INSL3 Antibody - BSA Free [NBP3-04435]

Immunohistochemistry-Paraffin: INSL3 Antibody - BSA Free [NBP3-04435]

Immunohistochemistry-Paraffin: INSL3 Antibody [NBP3-04435] - Paraffin-embedded human prostate using INSL3 antibody at dilution of 1:100 (40x lens).

Applications for INSL3 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:100

Immunohistochemistry

1:50-1:100
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS with 50% glycerol, pH7.3.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: INSL3

Insulin-like 3 (INSL3), a member of the insulin-like hormone superfamily, is specifically expressed in Leydig cells of the fetal and postnatal testis and in theca cells of the postnatal ovary. It is synthesized as a 131-amino acid preproprotein, which contains a 24-amino acid signal peptide. The human INSL3 gene is assigned to bands p13.2-p12 of the short arm of chromosome 19 with the similar organization to that of insulin and relaxin. INSL3 induces gubernaculum development in an androgen-independent way, while androgen-mediated regression of the CSL occurs independently from Insl3. Moreover, INSL3 is a ligand for LGR8 and INSL3-LGR8 mutations are believed to be associated with human cryptorchidism.

Long Name

Insulin-like 3

Alternate Names

Ley I-L, RLF, RLNL

Gene Symbol

INSL3

Additional INSL3 Products

Product Documents for INSL3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for INSL3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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